Introduction: Team-based learning (TBL) modules are essential components of our preclinical curriculum. This TBL module was developed to serve as an experiential exercise enabling first-year medical students to apply foundational concepts related to hemoglobin structure/function and acid-base balance to the pathophysiology of carbon monoxide poisoning. Methods: As with other TBL modules, students must first complete an advance-preparation reading assignment before attending the module. The module itself takes approximately 2 hours: 17 minutes for the Readiness Assurance phase (individual Readiness Assurance Test: 7.75 minutes, team Readiness Assurance Test: 9.25 minutes), 5-10 minutes for an intersession, and 90 minutes for the Application of Concepts phase. Results: Assessment outcomes are provided for each year of administration on a question-by-question basis in the appendix file entitled TBL Module.pdf. Discussion: This resource is directed primarily at preclerkship medical students and other health care professions students at comparable early levels of training. We have run the module for the past 4 years, the first three times near the end of the M1 fall semester in our Biomedical Foundations of Clinical Practice 2 course and the fourth time near the beginning of the M1 winter semester in our Heme/Lymph organ system course.
- Review the effects of carbon monoxide on binding and release of oxygen from hemoglobin.
- Discuss pathophysiological mechanisms of carbon monoxide poisoning.
- Explain how carbon monoxide poisoning can result in acid-base imbalance.
- Apply clinical presentation and laboratory test results to the diagnosis and initial management of carbon monoxide poisoning.
- Participate in the team-based learning activity in a professional and respectful manner.
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