Original Publication
Open Access

Acute Hemolytic Transfusion Reaction

Published: July 16, 2014 | 10.15766/mep_2374-8265.9834

Included in this publication:

  • Acute Hemolytic Transfusion Reaction - STAT.pptx
  • Transfusion Reaction Worksheet.pdf

To view all publication components, extract (i.e., unzip) them from the downloaded .zip file.

Editor's Note: This publication predates our implementation of the Educational Summary Report in 2016 and thus displays a different format than newer publications.


This simulation scenario focuses on diagnosing and managing acute hemolytic transfusion reaction in the emergency department. It includes a novel one-page evaluation tool entitled the Simulation Training Assessment Tool (STAT) to facilitate assessment and debriefing by the instructor. Training using this simulation scenario was conducted on March 27, 2013 for approximately 20 emergency medicine residents and four medical students. It resulted in increased awareness of acute hemolytic transfusions reactions and how to manage the life-threatening complications that may result.

Educational Objectives

By the end of the module, the learner will be able to:

  1. Recognize acute hemolytic transfusion reaction (AHTR) in an emergency department patient receiving blood transfusion.
  2. Confirm diagnosis through laboratory testing.
  3. Provide correct life-saving therapies to a patient with AHTR.
  4. Respond appropriately to systemic error of wrong blood transfusion.

Author Information

  • Jay Baker, MD: Madigan Army Medical Center
  • Luke Murphy, MD: Madigan Army Medical Center
  • Ben Good, MD: Madigan Army Medical Center

None to report.

None to report.


Baker J, Murphy L, Good B. Acute hemolytic transfusion reaction. MedEdPORTAL. 2014;10:9834. https://doi.org/10.15766/mep_2374-8265.9834